Aside from an interesting name, Nebido has some interesting uses and properties that make it one of the most unique testosterone based hormones in existence. It is essentially a long-form ester derivative of hormones normally used to treat men with low testosterone. It features the same ester of the hormone normally used in a hormone called Andriol. However, rather than being an oral steroid, Nebido is injectable, making it much more potent in terms of its administration and the effects of the hormone thereafter.
In terms of how long the steroid hormone has been on the market, it’s relatively young. Whereas a lot of other hormones have been on the market for much longer, Nebido has been on sale for approximately 13 years, going back to the year 2004. A company called Schering AG is responsible for bringing it to sale in the general marketplace. Unlike a lot of other popular drugs, it was approved for use as androgenic deficiencies, so this means that anyone whether they be a woman or man, they could use this drug to treat the lack of hormones in the system. This is a critical distinction to make, because again, this is a legal hormone in many territories, and there are plenty of people using this substance for therapeutic purposes. Despite this fact, it is of popular use for individuals that are trying to make strides and better their quality of life, which coincidentally, is primarily why most people use androgens in the first place.
In the United States specifically, it is still under questionable legal authority. The FDA never approved it for use, but a company called Indevus approved does own the rights to it in the United States. As of now, there is really no update as far as the legal status of Nebido is concerned, but the FDA still not advancing the hormone any further in the review process, and it remains illegal in the U.S. for unknown reasons, which in all honesty, may never be clarified due to the endless bureaucracy that is in charge of determining the fate of most drugs and hormones.
The truth is, this is a substance that is really intended and primarily used by those in therapeutic settings. Because it is a low ester form of testosterone, the truth is, it could be theoretically used as a performance enhancer. But because of the longer ester chain, this means that it will be absorbed and noticed a lot slower than other forms of testosterone, namely testosterone cypionate or testosterone enanthate. But due to its slow acting nature, it’s really not suited for any setting that is a performance-based capacity.
The only thing that really stands out about Nebido is that it’s a form of pure testosterone that’s attached to a very large Undecanoate ester. The aforementioned ester is attached to it to regulate the rate of release, making it tremendously slow in terms of the release duration. Despite being attached to it, it by no means affects its effectiveness or overall potency, and it ensures that it can constantly release a steady pulse rate of the hormone in a slow manner for the long haul. So again, this is going to still provide the benefits that any other form of the hormone would, but it just happens to be delivered in a slower manner.
In terms of how anabolic it is, it is no different than other testosterone compounds. It is rated as a 100 in terms of its androgenic capability, as are other forms of testosterone. Because of its ester makeup, it has one of the longest half-lives in existence as far as androgenic compounds go. This means that if you’re expecting the compound to be out of your system, for example, a concern of many athletes using a similar compound, you have to be fully aware that this is going to be in your system for a longer duration. The active half-life duration of Nebido is over three months, whereas other ester chains like test cypionate or test enanthate only have half-lives of around a week. This should emphasize in very big letters just how slow-acting Nebido can be, so again, if you want something that packs a punch in a quick time period, this is absolutely not the compound to use.
If you want to understand how Nebido works, you need to first understand how testosterone works. Testosterone is the primary androgen that is produced naturally in both men and women. Despite the fact it’s present in both sexes, men need it approximately 10 times as much as women do, and it plays a vital role for men given its greater quantity of presence. It plays a major factor specifically in terms of the sexual development of men and retention of muscle and strength. It also aids in aggression in focus, which are all critical qualities that make men who they are.
Just like any other kind of androgenic problem, you can notice the side effects of such a deficiency if you see a lack of aggression, decrease in strength or muscle mass, and other similar side effects. While these are not precise indicators of a possible androgenic deficiency, you can check once and for all by having an actual blood test done to assess your hormone levels. It is also important to understand that if you plan to use it for therapeutic purposes, you need to assess where your hormone levels stand. Once that’s completed, you can then definitely use Nebido to revitalize your testosterone levels.
The great thing about Nebido is it’s basically just a synthetic version of your body’s testosterone hormone, so it will bind to your androgen receptors no differently than your natural testosterone. Because you’d essentially be suffering from a condition where your body cannot supplant enough testosterone to handle its needs, Nebido will come into play to ensure that those needs are met expediently. If you plan to use it for performance enhancement, it shouldn’t be used for any longer than 16 weeks because of its slow-acting nature. However, as far as direct positive effects to expect from using Nebido, you can count on better nitrogen retention, enhanced levels of protein synthesis, increased IGF-1 production, great levels of red blood cells, and lower levels of glucocorticoids.
To have a better understanding of how the test can be used in a performance enhancement fashion, be sure to examine other kinds of compounds, but if you do have an overall understanding of how Nebido performs, you’ll have an awareness for what to expect from these compounds in most fashions.
If you’re suffering from the low test, then you already know the majority of the symptoms you’re experiencing. This is important to keep in mind because, all too often, people assume that because of these results that there is absolutely no need to use Nebido. No, if you are suffering from any of the following: lethargy, lack of sex drive, weakness, persistent stress and other issues, then you definitely do not want to bother with ignoring these symptoms any further. Once you start taking Nebido, you’re going to experience a lot more positive side effects, and many of these could be within a few weeks, despite the fact that Nebido is so slow-acting. Any of the issues related to lethargy, insomnia, erectile dysfunction, loss of strength, loss of muscle, loss of hair, depression, and a myriad of other symptoms can be fixed with just a little bit of testosterone supplementation. If you’re suffering from any of these symptoms of testosterone, you’re undoubtedly facing a very low quality of life. But rather than continuing to live with these sort of issues, you can immediately take action and do whatever it takes to make sure you improve and go beyond what you’re facing, which is a very important distinction to make compared to other issues you might be facing.
Many of these problems are not life-threatening by any means, but they can be annoying enough to really affect your quality of life in a manner that demands you change it up. And because it’s so easy to supplement with compounds like Nebido or other testosterone-based supplements, there is absolutely no need to put your body through that kind of anguish.
Even though your body certainly needs testosterone, it’s important to note that whenever you introduce an exogenous substance into your body, there are always going to be side effects. These are effects that should be noted and should you be aware of them, they won’t be as frustrating for you to experience or endure should they happen. This is very important to understand in comparison with other kinds of this hormone, because all too often, they can be very hard to pinpoint. But with a novice understanding, you should be in good shape to progress and make headway with this substance.
With any hormone that involves androgen receptors, there is always going to be the risk of estrogenic effects. This is because that whenever you introduce testosterone, they will aromatize, meaning that they interact with the aromatase enzyme, which converts them into estrogen. This interaction is very important to make note of because, in other circumstances, you’re going to need an AI (aromatase inhibitor) to lower the overall levels of your estrogen by shutting down the activity of the enzyme altogether. But in other instances, a SERM (selective estrogen receptor modulator) is going to act to prevent the estrogen from binding to receptor sites by acting as a buffer. Both do similar things, but the latter option is going to be your first option since it does not manipulate entire hormone levels. Estrogen is always going to be a risk factor, but monitor your levels because it can affect cholesterol, cause water retention, or even result in drastic swings in mood or personality.
Because it’s such a powerful androgen, you have to be aware of the side effects that are androgenic in nature. These specifically rate to the possibility for you to lose hair as testosterone is often converted into dihydrotestosterone, which is activated by the 5-alpha-reductase enzyme. This in turn leads to things like increased oiliness of the skin, increased levels of hair loss, and the acceleration of male pattern baldness if you’re someone who is genetically predisposed to suffering from male pattern baldness. There are 5AR inhibitors that can be taken, but because most of the androgenic side effects aren’t as serious, most men typically ignore these kinds of side effects.
Because most people suffer from common side effects that lead to a number of other issues in their cardiovascular system, it’s important to be aware of them. High blood pressure is something that is tremendously common with any new androgenic supplement, but you can reduce the odds of this happening if you can stave off the water retention, which is very closely linked to the levels of estrogen in the body. If you can control estrogen, you can most likely contain any severe effects of high blood pressure for sure. If you’re using low doses of Nebido, you shouldn’t expect to see any major shifts in your cholesterol levels. However, if your cholesterol is on the borderline, then that could be a major issue that you’d have to be keenly aware of. This is why when supplementing with Nebido or any other androgen, keeping a clean, healthy lifestyle is of the utmost importance.
Thankfully, because Nebido and other kinds of injectable hormones are not hepatoxic, you will not have to worry about any sort of liver or organ damage.
Because it’s so slow in terms of its effects, you don’t have to go overboard when it comes to using Nebido. You can get away with using 1,000 mg every 12 weeks, and after the first six weeks, you can get away with one more 1,000 mg dose just to add some space in-between the gap. Because it’s so slow acting and combined with its potency, only a few injections of it will yield tremendous benefits. This means fewer headaches for you having to inject all of the time, and you can rest assured that you’re being saturated with a very effective hormone that is going to alleviate all of your low testosterone symptoms.
Because of the fact, Nebido is really slow acting, there is not much of a demand for it in the black market. It’s also a very slow acting drug, so again, people aren’t exactly going out of their way to sell it or make a black market, UGL versions of it. Most likely, you can find it somewhere on the European markets, but it’s going to be virtually non-existent in any U.S. market. This is a very rare drug to find, and if you do find it, don’t expect it to be available in large quantities, either. You can rest assured that if you’re looking for other kinds of testosterone that are better served as performance enhancers, then you can find those elsewhere on the market in readily available quantities.
To recap, you’re going to find that Nebido is one of the best forms of testosterone out there. It has a very slow acting ester profile, so that means it does not operate in the same duration of capacity as other hormones. This makes it extremely hard to find and assuming you are able to find it, you’re not going to glean much from it in a productive sense for performance enhancement. This is why you need to consider using different compounds or esters if you’re truly serious about something that is going to improve your performance capacity. That said, there are a lot of uses for Nebido and if you do plan on making the best of them, you can really see a lot of benefits by using it for a long period of time in a therapeutic fashion.