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Stanozolol is subject to non-medically supervised off-label use by some athletes for its anabolic properties frequently presenting with concomitant reduction of body fat. Stanozolol is a modified derivative of dihydrotestosterone (DHT) and thus not aromatized to oestrogens via the aromatase class of enzymes. Bodybuilders frequently misuse the term “dry” in describing their joint pain while using stanozolol either orally or via IM injection of an aqueous suspension; a reference to their perceived reason for an increase in joint pain. Rather, stanozolol as a DHT derivative can selectively compete with progesterone and other natural and synthetic progestins (nandrolone) for progestin receptors; yielding a reduction in progesterone mediated anti-inflammatory processes and presenting patients with a perception of increased joint discomfort. Commonly used by athletes and bodybuilders alike to lose fat while retaining lean body mass. It is usually used in a “cutting or leaning out” cycle, to help preserve lean body mass while metabolizing adipose. Stanozolol is subject to extensive hepatic biotransformation by a variety of enzymatic pathways. The primary metabolites are unique to stanozolol and are detectable in the urine for up to 10 days after a sin250gle 15 mg oral dose.
Winstrol (stanozolol) is a relatively low androgenic steroid which does not seem to aromatize. Winstrol can be toxic to the liver in excessive dosages. Winstrol is a popular all purpose steroid; many stack with Primobolan or Parabolan for cutting, others stack it with testosterone for size and strength gains. Women often use winstrol but occasionally it can cause virilization, even at low dosages. Winstrol gives a solid muscle gain and an over proportionally strong strength, which usually remains after use of Winstrol is discontinued.
Structurally Winstrol (stanozolol) is not capable of converting into estrogen. Likewise an anti estrogen is not necessary when using this steroid, gynecomastia not being a concern even among sensitive individuals. Since estrogen is also the culprit with water retention, instead of bulk Winstrol produces a lean, quality look to the physique with no fear of excess subcutaneous fluid retention. This makes Winstrol a favourable steroid to use during cutting cycles, when water and fat retention are a major concern.
Stanozolol is a derivative of dihydrotestosterone, although its activity is much milder than this androgen in nature. While dihydrotestosterone really only provides androgenic side effects when administered, stanozolol instead provides quality muscle growth. The anabolic properties of stanozolol are still mild in comparison to many stronger compounds, but it is still a reliable builder. Its efficacy as an anabolic could even be comparable to Dianabol , however stanozolol does not carry with it the same tendency for water retention. Stanozolol also contains the same c17 methylation we see with Dianabol, an alteration used so that oral administration is possible.
Structurally stanozolol is not capable of converting into estrogen. Likewise an anti estrogen is not necessary when using stanozolol, gynecomastia not being a concern even among sensitive individuals. Since estrogen is also the culprit with water retention, instead of bulk stanozolol produces a lean, quality look to the physique with no fear of excess subcutaneous fluid retention. This makes stanozolol a favourable steroid to use during cutting cycles, when water and fat retention are a major concern.
For men the usual dosage of stanozolol is 15-25 mg. per day for the tablets, preferably taken in two-three doses over the day. Stanozolol is often combined with other steroids depending on the desired result. For bulking purposes, a stronger androgen like Dianabol or Anadrol , is usually added. Here stanozolol will balance out the cycle a bit, giving a good anabolic effect with lower overall estrogenic activity than if taking such steroids alone.
Women will take somewhere in the range of 5-l0 mg. daily. Although female athletes usually find stanozolol very tolerable, the injectable is usually off limits. They risk androgenic build-up, as a regular 50 mg. injection will provide much too high a dosage. Here the tablets are the general preference. Although stanozolol is only moderately androgenic, the risk of virilization symptoms should remain a concern.
For all anabolic steroids, the following should be considered; tell your doctor if you have ever had any unusual or allergic reaction to anabolic steroids or androgens. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Anabolic steroids are not recommended during pregnancy. They may cause the development of male features in the female fetus and premature growth and development of male features in the male fetus. Be sure you have discussed this with your doctor.
It is not known whether anabolic steroids can cause problems in nursing babies. There is very little experience with their use in mothers who are breast-feeding. Anabolic steroids may cause children to stop growing. In addition, they may make male children develop too fast sexually and may cause male-like changes in female children. When elderly males are treated with anabolic steroids, they may have an increased risk of enlarged prostate or cancer of the prostate.
With the structural (c17-AA) alteration, the tablets will place a higher level of stress on the liver than the injectable. During longer or higher dosed cycles, liver values should therefore be watched closely through regular blood work. Such stress would of course be amplified when adding other c17-AA oral compounds to a cycle of stanozolol. When using such combinations, cautious users would make every effort to limit the length of the cycle not to be longer than a maximum of 6-8 weeks. It is also of note that stanozolol has been linked to strong adverse changes in the cholesterol levels. This side effect is common with anabolic steroid therapy, and obviously can become a health concern as the dose/duration of intake increase above normal. The oral version should have a greater impact on cholesterol values than the injectable due to the method of administration, and may therefore be the worse choice of the two for those concerned of this side effect. The oral use of stanozolol can also have a profound impact on levels of SHBG (sex hormone-binding globulin). This is characteristic of all anabolic/androgenic steroids, however its potency and form of administration makes oral stanozolol particularly noteworthy in this regard. Since plasma binding proteins such as SHBG act to temporarily constrain steroid hormones from exerting activity, this effect would provide a greater percentage of free (unbound) steroid hormone in the body. This may amount to an effective mechanism in which stanozolol could increase the potency of a concurrently used steroid. Proviron has an extremely high affinity for SHBG. This affinity may cause Proviron to displace other weaker substrates for SHBG, another mechanism in which the free hormone level may be increased. Adding stanozolol and Proviron to a testosterone cycle may therefore prove very useful, markedly enhancing the free state of this potent muscle building androgen.